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Topics covered include: Basic anabolic and catabolic pathways in microbial cells, glycolysis, Krebs cycle, oxidative phosphorylation, synthesis of amino acids, nucleic acids, fats, carbohydrates, products of fermentation – ethanol, lactic acid. In vivo culture of animal cells: applications of animal cells; production of recombinant proteins, stem cells, bioethical issues regarding use of human stem cells. Stem cell and cell based therapy applications including chimeric antigen receptor (CAR)-T cells. Cell based model systems in disease modelling. (K.English, K.Kavanagh)
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