Courses :: Module, PHARMACEUTICAL CHEMISTRY I

	Overview
	Formulation Chemistry and Drug Delivery Systems, Structural Elucidation of Bio-molecules. This module examines two important areas of pharmaceutical chemistry: (i) Formulation Chemistry and Drug Delivery Systems. The course introduces the principles and purpose of formulation chemistry and drug delivery systems and the main physicochemical aspects relevant to formulation. It reviews the different types of dosage forms according to the route of administration, including modified and controlled release drug delivery systems, and the application of liposomes and nanoparticles to targeted drug delivery. The different components of a pharmaceutical formulation and the factors to consider in the choice of a suitable dosage form are discussed. (ii) Structural determination of bio-molecules: Material covered includes: Structure of bio-molecules for example, proteins, nucleic acids, carbohydrates and fats; chemical analysis of proteins and peptides, ESI, MALDI and Tandem Mass spectrometry, NMR spectroscopy and hardware development, FT-NMR, 2-D NMR, X-ray crystallography.

Overview

Formulation Chemistry and Drug Delivery Systems, Structural Elucidation of Bio-molecules.

This module examines two important areas of pharmaceutical chemistry:
(i) Formulation Chemistry and Drug Delivery Systems. The course introduces the principles and purpose of formulation chemistry and drug delivery systems and the main physicochemical aspects relevant to formulation. It reviews the different types of dosage forms according to the route of administration, including modified and controlled release drug delivery systems, and the application of liposomes and nanoparticles to targeted drug delivery. The different components of a pharmaceutical formulation and the factors to consider in the choice of a suitable dosage form are discussed.
(ii) Structural determination of bio-molecules: Material covered includes: Structure of bio-molecules for example, proteins, nucleic acids, carbohydrates and fats; chemical analysis of proteins and peptides, ESI, MALDI and Tandem Mass spectrometry, NMR spectroscopy and hardware development, FT-NMR, 2-D NMR, X-ray crystallography.

	Learning Outcomes
	On successful completion of the module, students should be able to: Discuss a number of factors that are important to the techniques commonly used to obtain structural information on bio-molecules. Be able to analyse the mass spectrum of a bio-molecule. Be able to analyse or predict the NMR spectrum of simple bio-molecules. Demonstrate an understanding of the basic principles underlying the needs for drug delivery systems and dosage forms. Describe the most common types of dosage forms. Discuss the physicochemical properties relevant to formulation and drug delivery systems. Have a good knowledge of the most important types of drug delivery systems and drug targeting.

Learning Outcomes

	Autumn Supplementals/Resits
	Continuous assessment will be carried forward to the Autumn. University scheduled written examination (Autumn): 90 minutes

Autumn Supplementals/Resits

	Pre-Requisites
	CH201, CH202, CH203

Pre-Requisites

	Timetable
	This timetable is not currently available, please contact the Chemistry Department.

Timetable

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Courses / Module

PHARMACEUTICAL CHEMISTRY I